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146,215 articles from EurekAlert

Inflammation is a hallmark of many health conditions, but quantifying how the underlying biology of inflammation contributes to specific diseases has been difficult. For the first time, UNC School of Medicine researchers and colleagues now report the development of a new technology to identify white blood cells called neutrophils that are primed to eject inflammatory DNA into the circulation via a process called NETosis.

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson's disease. A disturbed relationship to these 'bodyguards' leads to cell damage and the formation of Lewy bodies typical for Parkinson's disease. The findings by researchers from the University of Basel's Biozentrum have been published in Nature.

When given the new drug to reduce inflammation, senile mice had fewer signs of dysfunctional brain electrical activity and were better able to learn new tasks, becoming almost cognitively adept as mice half their age. Other findings indicate two practical pathways -- measuring the leakiness of the blood-brain barrier via MRI and abnormal electrical brain activity via EEG -- that can be used to screen people for a leaky BBB.

CF Plus Chemicals, a spin-off of ETH Zurich, IOCB Prague, and IMIC have developed a new technology called CF LINK for site-selective bioconjugation of proteins and also their structural characterization. The recently published, patent-pending technology allows to selectively prepare protein conjugates via their tryptophan residues and perform posttranslational modification of aromatic amino acids. Furthermore, it can also be used as a tool for the mapping of protein surfaces and studies of protein-protein interactions.

New data from the Parker Solar Probe, which got closer to the sun than any other spacecraft, allowed physicists to map the source of a major component of the solar wind that continually peppers Earth. The slow solar wind seems to emerge from coronal holes along the sun's equator. Data also reveal strange magnetic field reversals that could be accelerating solar wind particles, and an unexpectedly dense shroud of comet dust around the sun.

Scientists at the National Institutes of Health found that women who use permanent hair dye and chemical hair straighteners have a higher risk of developing breast cancer than women who don't use these products. The study published online Dec. 4 in the International Journal of Cancer and suggests that breast cancer risk increased with more frequent use of these chemical hair products.

Probiotics -- or 'good bacteria' -- have been used to treat infant colic with varying success. In a new trial published in the journal Alimentary Pharmacology & Therapeutics, investigators have shown that drops containing a particular probiotic strain (Bifidobacterium animalis subsp. lactis BB-12) reduced the duration of daily crying by more than 50% in 80% of the 40 infants who received the probiotic once daily for 28 days, with beneficial effects on sleep duration and on stool frequency and consistency.